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Epilepsy- Diagnosis and Medical Management

Investigation

  1. Hematology
  2. Biochemical analysis (electrolytes, urea, and calcium)
  3. Chest X-ray
  4. Electroencephalogram (EEG)
  5. CT scan
  6. MRI
  7. Positron emission tomography (PET) 
  8. Single-photon emission computed tomography (SPECT)

Medical Management

  • If the patient goes 3 years without an attack, withdrawal of therapy should be recommended.
    Drug for epilepsy

  • The commonest drugs used:
    • Carbamazepine
    • Sodium Valproate/valproic acid
    • Phenytoin (chronically produce facial features and hirsutism (looks like man face)
    • Phenobarbitone
    • Lamotrigine
    • Gabapentin
    • Topiramate
    • Tiagabine
    • Zonisamide
    • Oxcarbazepine
    • Levetiracetam
    • Lorazepam
    • Diazepam
    • Ethosuximide
    • Clonazepam


👉The broadest anti-epileptic drug is Sodium Valproate.


Drugs for partial epilepsy

1st – Carbamazepine

2nd – sodium Valproate


Drugs for Tonic-clonic Generalised Epilepsy

1st – Sodium valproate

2nd – Lamotrigine


Drugs for Generalised Absence Epilepsy

1st – Ethosuximide

2nd – Sodium valproate


Drugs for Myoclonic Epilepsy

1st – Sodium valproate

2nd – Clonazepam


Drugs for Status Epilepticus

1st – Diazepam or Lorazepam

2nd – phenytoin or Fosphenytoin


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